Every player has their own thing, unique tics and tells, and once you learn what to look for it’s quite entertaining to watch players and pick up on their unique tics and tells. Even in the best players there is commonly a few involuntary tells that you can watch for. Even the first time you sit down with someone there are often small give aways. As a general rule, when a player acts strong, he is probably weak, and when acting weak, he is probably holding a really strong hand.

I Have a Good and Strong Hand

Players acting uninterested in a hand, while still in it. Usually this is a sign of a strong hand. The player is pretending not to be excited about his cards, while in fact he or she is the opposite.

Nervous and Shaky Hands

During a hand, and if you notice that a player’s hands are shaking or acting nervous, as they are placing their bet, they probably has gotten a really really good hand.

Fast or Uneven Breath

Players that is aware of their tells can control nervous and shaking hands, but it's harder to control the automatic breath, as the heart rate goes up on pocket aces or hitting the flush  on the flop. If you can detect breathing speed and whether changing, often they have an excellent hand.

Sighing and Shrugging

Player that show sighing or shrugging, trying appear uninterested and comments with things like “I guess I’ll call,” or even “I don't really know why am I calling” etc. he or she is most likely putting on a show, overacting trying to hide a big hand.

Looking at Chips after Looking at Hole Cards

When a player looks down and sees strong hole or pocket cards, he or she may take a look at their chips to see just how much they can bet, hence be aware as it is possibly a strong hand in the making.

I Have a Weak Hand

If an opponent is staring you down, he or she is most likely trying to represent strength. Usually though, they hold a weak hand, even though it may be decent cards, often it’s something that can be beaten or pushed into a fold during the game.

Holding their Breath

Often, inexperienced players will hold their breath if they are bluffing, i.e. trying to appear strong on a weak hand they freeze in an attempt to control not giving up a tell.

I Have a Drawing Hand

If the flop shows the possibility of giving someone a flush or straight draw, watch for players that checks their hole cards after the flop. Commonly they are checking to see if they have the hand. Regardless of the flop, they are not likely to have a flush or straight at that point, if they did, they would not have to check, instead they are likely to check whether they has a draw to it.

Taking too Long Before Calling a Bet

When a player looks into the pot and appears to do head calculations (probably is), they most likely are figuring out the pot odds to see if it’s worth it, i.e. trying to catch the cards needed to complete drawing a hand.